Cross-Contamination Cross-contamination occurs when workers spread contaminants around the worksite and into their homes by soiled clothing, shoes, and skin contact. Contaminants can be transferred to the items workers touch, sit on or walk on. Using good personal hygiene at work by hand washing, showering, and changing dirty clothing and shoes can help prevent cross contamination. Workers that handle chemicals and contaminants in the workplace are aware that the use of personal protective equipment (PPE) such as gloves, safety glasses, respirators, coveralls, and boots, can reduce or eliminate their exposures. PPE can act as a barrier against the contaminants and protect the...